P362 Employment and life choices for PwCF in Wales – 10 years on

In 2013, we demonstrated that ppFEV1 and gender were associated with employment status in people CF (PwCF) attending the All Wales Adult Centre (AWACFC). As life has changed for many PwCF, a longer lifespan introduction of highly effective modulator therapies (HEMT) wanted to assess changes education our patient cohort since 2013. Demographics, data collected at annual review 2022 (n = 312) reviewed compared 2013 223). Compared AWACFC population grown (312 (181 male) vs 223 (127 male)), risen age (mean 33 29 years) 78 66%). The number PwCF employed increased 17% (58 41%), 5% performing permitted work (≤16 hours) alongside disability benefits. Retirees have also (4% 1%). Full time caregiving by 11% (17% 6%). 2022, 12% full 22% 8% studying undergraduate level. dependent on benefits dropped 12%, from 30% 18% 2022. Of those benefits, 5.1% had non-CF additional needs, 5.7% < 50% 7% ≥50%, no or differences. Increasing numbers are employed, working as homemakers, rise able retire work. This is likely continue wider access HEMT. Permitted Work schemes enabled little experience develop confidence, self-esteem skills which they been transfer into more meaningful jobs. With university it career options will broaden future. Available support become parents, enter workplace build careers must reflect current future population.